Like sawman said a well placed shot is key head or neck. I have put a .270 and 2 44 mag rounds federal hydroschoks in one 275-300 pounder. He was charging me the 270 sat him back on his Hinds, the first 44 turned him away from about 10 feet and he took the second 44 and ran off. This is the one I killed when the other 2 charged me.
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